Generic Name:Temsirolimus

Temsirolimus is a drug used to treat advanced renal cell cancer (kidney cancer). It comes as an injection that is administered intravenously by your healthcare provider once a week. Although this can be an effective medicine, it may not be suitable for some people who are taking certain medications or who have certain medical conditions. This medication is strictly sold by prescription. Temsirolimus is prescribed for the treatment of advanced renal cell carcinoma (kidney cancer) in adults. It works by blocking the action of certain enzymes in the body, which helps to slow down the growth and spread of the cancer. There are also some possible other, uses for temsirolimus, such as treating mantel cell lymphoma, which is a type of non-Hodgkin's lymphoma.

How to Use Temsirolimus Injections

  • This medication is given as an injection into a vein (an intravenous, or IV, injection) once a week.
  • A healthcare provider will administer the injections in a healthcare setting, such as a hospital or clinic.
  • The injections are given slowly, over a period of 30 to 60 minutes. This is called an intravenous infusion.
  • You will receive a different medication via IV about 30 minutes before your dose of temsirolimus to help prevent allergic reactions to temsirolimus.

Cautions before Use Temsirolimus Injections

  • Temsirolimus can increase your risk for developing infections, including potentially serious fungal, bacterial, or viral infections.
  • Some people receiving temsirolimus may experience allergic reactions, including potentially life-threatening reactions.
  • Temsirolimus may cause an increase in blood glucose or blood sugar that may require treatment with medications.
  • People may develop high blood lipids high cholesterol and triglycerides during Temsirolimus treatment, which may require treatment with a high cholesterol medication.
  • Temsirolimus may cause bowel perforation, which is a hole in the bowel. This problem can be life-threatening.
  • Wounds may not heal properly while you are undergoing Temsirolimus treatment.
  • Temsirolimus may increase the risk for bleeding in the brain. People who have central nervous system tumors such as brain.tumors or who take anticoagulant medications have an even higher risk with this medication.
  • This medicine could be dangerous if taken during pregnancy as it may harm the unborn child.

Temsirolimus Injections Side Effects

The side effects which may arise due to the usage of Temsirolimus are as follows:

  • Yellowing of the skin or whites of the eyes
  • Sores inside the mouth or throat
  • Painful urination, blood in your urine, or urinating less often than usual or not at all
  • Swelling of the arms, hands, legs, ankles, or feet
  • Warmth, redness, pain, or tenderness of one or both legs
  • Confusion or problems thinking, walking, or talking
  • Unusual bleeding or bruising
  • Fatigue, pale skin, dizziness, or shortness of breath, which could be signs of anemia

Interactions and Overdose of Temsirolimus Injections

Echinacea, cyclosporine, live vaccinations, and certain other drugs may cause negative interactions when combined with temsirolimus. Some of these reactions can increase the risk for potentially serious side effects or decrease the effectiveness of the medicines. Your healthcare provider may need to monitor you more closely if you are undergoing temsirolimus treatment, and adjust your dosage amounts as needed.

In case of any over dosage people should seek immediate medical support.


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