Dapsone is used to treat a certain type of skin disorder medically known as dermatitis herpetiformis. It is also used with other drugs to treat Hansen's disease. Dapsone belongs to a class of drugs known as sulfones. It works by decreasing swelling and stopping the growth of bacteria. This medication will not work for viral infections like common cold and flu. Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. The other uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. In addition, it is found in studies that Dapsone is majorly used for the treatment of leprosy. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat or prevent a certain lung infection due to HIV pneumonia, to prevent a certain brain infection due to HIV toxoplasmosis, and to treat skin conditions in certain immune system disorders

How to Use

Take this medication by mouth with or without food, usually once daily or as directed by your doctor. Dosage is based on your medical condition and response to treatment. In children, the dosage is also based on age and weight. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Tell your doctor if your condition worsens. Medications for heartburn or reducing stomach acid like large amounts of antacids, ranitidine or famotidine may prevent full absorption of Dapsone into your bloodstream, possibly reducing its effectiveness. Therefore, separate your dose of Dapsone from your doses of any of these products by at least 2 hours.

Cautions before Use

The cautions that are needed to take with Dapsone are as follows:

  • Before taking dapsone, tell your doctor or pharmacist if you are allergic to it; or to similar drugs such as sulfoxone; or if you have any other allergies
  • Before using this medicine, consult your doctor or pharmacist if you have severe anemia
  • People with a medical history of liver disease
  • People with a medical history of certain blood disorders like G6PD deficiency
  • People with a medical history of heart disease
  • People with a medical history of lung problems
  • People with high blood sugar
  • Pregnant women and breast feeding mothers

Dapsone Side Effects

The side effects that may occur by using Dapsone are as follows:

  • Nausea
  • Vomiting
  • Dizziness
  • Blurred Vision
  • Chest Pain
  • Unusually fast heartbeat
  • Unusually fast breathing
  • Bluish lips or skin
  • Mental or mood changes
  • Muscle weakness
  • Difficulty in urinating
  • Allergic rash

Reactions and Overdose

This drug may rarely cause very serious low blood counts bone marrow suppression or liver disease therefore those patients are suffering from liver problem should not take this medicine.

Before using this medication, tell your doctor or pharmacist of all prescribed and non-prescribed or herbal products you are using and adjust the doses according to it.

It may react with folic acid antagonists such as pyrimethamine, nitrofurantoin, primaquine.

It can also react with birth control pills.

Overdosed patients may have the symptoms of seizures, bluish skin cyanosis, sudden vision changes, and sudden loss of vision and seek medical attention.


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