Locoid cream and ointment both contain the active ingredient hydrocortisone butyrate, which is a type of medicine called a topical corticosteroid. It is also available with the name of Locoid Lipocream.

Locoid is a type of Corticosteroids, and these medicines used for reducing inflammation. The active ingredient of Hydrocortisone butyrate is classed as a potent corticosteroid. It is prescribed to treat severe inflammatory skin disorders such as eczema and psoriasis that have not responded to weaker corticosteroids.

Inflammation of the skin happens because of allergy or irritation of the skin, and caused by the release of various substances that are important in the immune system. These substances cause blood vessels to widen and result in the irritated area becoming red, swollen, itchy and painful, such as is seen in dermatitis or eczema.

When Locoid skin cream is applied to the skin, it works by acting inside the cells to decrease the release of these inflammatory substances. This reduces swelling, redness and itch.
There is a range of potencies of corticosteroids applied to the skin.

How to use Locoid Cream

  • Locoid cream and ointment are for external use on the skin only.
  • The cream or ointment should be applied thinly and evenly to the affected area(s
  • Avoid getting the medicine in the eyes, or in contact with the inside of the mouth or nose. Rinse with cold water if accidental contact occurs.
  • Wash your hands thoroughly after applying this medicine, unless the hands are the area being treated.
  • If your doctor has advised you to use dressings with this medicine, the skin should be cleansed before applying the cream/ointment under a fresh dressing.
  • If Locoid is used long-term, on large areas of skin, raw or broken skin, it may form severe side effects.

Cautions before Use Locoid Cream

The cautions, which are needed before taking this medication, are as follows:

  • Bacterial skin infections, such as impetigo
  • Fungal skin infections such as thrush, ringworm, athlete’s foot
  • Viral skin infections, such as chickenpox, shingles
  • cold sores
  • Herpes simplex
  • Acne
  • Chronic inflammatory disorder of the facial skin known as acne rosacea
  • Inflammatory rash around the mouth
  • Widespread plaque psoriasis

Locoid Cream Side effects

The side effects, which may occur due to the use of Locoid skin cream, are as follows:

  • Skin irritation at affected area, such as burning, itching and redness
  • Allergic inflammation of the skin
  • Thinning of the skin
  • Changes in skin pigmentation
  • Stretch marks (striae).
  • Groupings of fine blood vessels becoming prominent under the skin (telangiectasia)
  • Prolonged use of this medicine on extensive areas of skin, broken or raw skin, skin folds or underneath airtight dressings may on rare occasions result in enough corticosteroid being absorbed to have side effects on other parts of the body, for example a decrease in the production of natural hormones by the adrenal glands

Locoid Cream Reactions and Overdose

Before using this medication, ask your doctor or pharmacist about all prescribed and nonprescribed or herbal products you are using as it may cause reactions with them. It is better not to use any kind of moisturizer or cream with Locoid skin cream.

Locoid skin cream may be harmful if swallowed. If overdose or swallowing is suspected the patient should be taken to the medical center immediately.


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