Metrogel skin cream or lotion is used for skin problems and other ailments related to variety of different bacterial skin infections. The active ingredient of Metronidazole in it is commonly prescribed to treat several types of bacterial and parasitic infections. As an antibiotic, it works to fight infections by entering bacteria or parasite cells and producing free radicals, molecules that can damage and destroy cells. The medication comes in many different forms, including tablets, capsules, skin creams and lotions, and vaginal creams, depending on the particular product.

In order to work, Metrogel skin cream must enter the bacteria or parasite cell. The cells then cause a chemical reaction to occur with the medication. This reaction produces free radicals, molecules that can damage and destroy cells. This is presumably how the active ingredient of Metrogel works to kill bacteria or parasites.

How to Use Metrogel Cream

  • This medication comes in several different forms. The particular directions for each product can vary substantially, so be sure to refer to the information for your specific product.
  • If you are using Metrogel skin cream, then apply the cream as prescribed and should be applied in lesser amounts in the affected area.
  • You can take regular, short-acting Metrogel tablets or capsules with food or on an empty stomach. However, long-acting, extended-release Metrogel tablets must be taken on an empty stomach, at least one-hour before or two hours after a meal.
  • For the medication to work properly, it must be taken as prescribed. Do not miss doses or stop taking this antibiotic earlier than your healthcare provider recommends, as bacterial resistance may develop.

Cautions before use Metrogel Cream

  • It is a standard recommendation to avoid alcohol while taking Metrogel, although recent research suggests that the medication might not actually interact significantly with alcohol.
  • Metrogel can cause seizures.
  • Metrogel can cause nerve problems, especially in the hands and feet. You may develop numbness, paralysis, or any unusual sensations in your hands or feet.
  • If you have liver disease, your body may not metabolize this medication as well as it should.
  • Metrogel can worsen a pre-existing yeast infection such as thrush or a vaginal yeast infection.

Metrogel Cream Side Effects

Some of the possible metrogel side effects are thought to include:

  • Headaches
  • Vaginal irritation or infection
  • Nausea, vomiting, or stomach pain
  • Metallic taste in the mouth
  • Bacterial infections
  • Flu like symptoms such as a fever and chills
  • Genital itching
  • Dizziness
  • Diarrhea or constipation
  • Runny or stuffy nose
  • Sinus infection
  • Sore throat
  • Painful menstrual periods
  • Vaginal yeast infections
  • Dry mouth
  • Urinary tract infection (UTI), such as a bladder infection

Metrogel Cream Reactions and Overdose

Taking disulfiram, cimetidine, or certain other medications with metronidazole, drug interactions could occur. It may be dangerous if taken with alcohol or any kind of seizure medicines. Metronidazole can increase the level of lithium in your blood, increasing your risk for lithium toxicity.

Dangerous overdose affects may rise if swallowed, if this happens the patient must seek medical care. In case of the tablets overdose effects may rises into nausea, vomiting and co ordination problems.


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