This medication is used along with controlled ultraviolet light (UVA) to cause a return in skin color in patients with a certain skin condition vitiligo. Oxsoralen works by making the skin more sensitive to UVA light. This combination helps to increase the number of pigment-producing cells or melanin in the skin. This medication is not recommended for use in children younger than 12 years. This medication is used along with controlled ultraviolet light (UVA) to help control severe psoriasis. Oxsoralen works by making the skin more sensitive to UVA light. This combination helps to slow the overgrowth of skin cells. The dosage of Oxsoralen is based on your weight, medical condition, and response to treatment. The amount and time of UVA light for each treatment is based on your skin type and response to treatment. You may have UVA light treatments 2 to 4 times a week when you first start and then less frequently as your condition improves.

How to Use Oxsoralen Cream

This medication is applied by a health care professional to affected areas of the skin before your UVA light treatment. The frequency of treatment is based on your medical condition and response to treatment. After treatment with Oxsoralen and UVA light, protect the treated area from sunlight (including sunlight through windows) for several days. This will prevent the treated area from getting too many UVA rays, which could lead to sunburns. If you cannot avoid sunlight on the treated area, wear clothing over the area and/or sunscreen, which blocks out UVA light. Consult your doctor or pharmacist for information on how long to protect the treated area and which sunscreen to use. You may start to see improvement in your skin color after a few weeks of treatment but it may take 6 to 9 months to get the full benefit.

Cautions before Use Oxsoralen Cream

The cautions, which are to be followed, are as follows:

  • Before using Oxsoralen, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  • People with a medical history, that make you sensitive to light skin cancer
  • People with a medical history of melanoma,
  • People with a medical history basal cell or squamous cell carcinomas
  • People with a medical history coal tar or UVB treatment,
  • People with a medical history radiation treatment and arsenic treatment
  • Pregnant women should not take this medication

Oxsoralen Cream Side effects

The side effects, which may arise due to the use of Oxsoralen, are as follows:

  • Signs of an allergic reaction
  • Hives
  • Difficulty breathing;
  • Swelling of your face, lips, tongue, or throat
  • Skin redness
  • Severe Dizziness

Oxsoralen Cream Reactions and Overdose

Before using this medication, ask your doctor or pharmacist about all prescribed medicines and nonprescribed or herbal products you are using as it may cause reactions with them.

This drug may react with sulfa antibiotics like sulfamethoxazole, fluoroquinolone antibiotics like ciprofloxacin, thiazide diuretics like hydrochlorothiazide, tetracycline antibiotics like doxycycline, coal tar, griseofulvin.

Oxsoralen may be harmful if swallowed. If overdose or swallowing is suspected the patient should be taken to the medical center immediately.


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