Refissa skin cream is a treatment used in the problems of acne and other skin problems. It has the active ingredient of Tretinoin, which is a derivative of vitamin A. Topical tretinoin is used in the treatment of mild to moderate acne and on skin that has been damaged by excessive exposure to the sun. Tretinoin belongs to a class of medications called retinoids. Refissa skin cream irritates the skin and causes the cells of the skin to grow or divide and die more rapidly, increasing the turnover of cells.

This same medication is available with other brand names of Renova and Retin-A. Refissa skin cream may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Other forms of this medication are used to improve the appearance of the skin and minimize fine wrinkles.

How to Use Refissa Cream

Gently clean the affected skin with a mild or soap free cleanser and pat dry. Use your fingertips to apply a small amount of Refissa skin cream about the size of a pea in a thin layer, usually once daily at bedtime or as directed by your doctor. A gauze pad or cotton swab can be used to apply the liquid. For some preparations, you should wait 20-30 minutes after cleaning your face before applying this medication. Consult the label directions, the Patient Information Leaflet, or your pharmacist if you have any questions. Use this medication on the skin only. Do not apply to the inner lip area or inside the nose or mouth. This medication is available in different strengths and forms such as gel, cream and solution.

Cautions before Use Refissa Cream

The cautions, which are to be taken while using Refissa skin cream, are as follows:

  • Before using this medication, tell your doctor or pharmacist your medical history, especially of eczema on the skin.
  • Use of Refissa skin cream may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps.
  • Before using Refissa skin cream tell your doctor or pharmacist if you are allergic to Tretinoin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  • Avoid electrolysis, waxing and chemical depilatories for hair removal on the treated areas while using this product. If you have recently used products containing sulfur, resorcinol or salicylic acid, use Refissa with care.

Refissa Cream Side effects

The side effects, which may occur due to the usage of Refissa skin cream, are as follows:

  • Extreme Dizziness
  • Allergic rashes
  • Trouble in breathing
  • Blistering, crusting, severe burning or swelling of the skin
  • Eye redness and watering or conjunctivitis
  • Eyelid swelling
  • Itching and redness on the skin
  • Scaling
  • Mild burning
  • Worsening of acne

Refissa Cream Reactions and Overdose

Before using this medication, ask your doctor or pharmacist about all prescribed drugs and nonprescribed or herbal products you are using as it may cause reactions with them. Refissa may interact with products containing alpha hydroxy acid, products containing glycolic acid, hair perming solutions, alcohol, lime, menthol-containing products, fluoroquinolones such as ciprofloxacin, tetracyclines and thiazide water pills.

Refissa skin cream may be harmful if swallowed. If overdose or swallowing is suspected the patient should be taken to the medical center immediately.


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