Regranex skin cream or gel is a topical medication used for the treatment of various skin ailments. It contains Becaplermin in the form of a gel which is applied topically to diabetic ulcers in the lower limbs like on foot, ankle, and leg to promote healing of the ulcers. It belongs to a class of drugs called platelet-derived growth factors or PDGFs. Designed to mimic naturally occurring PDGF, Regranex is fabricated using recombinant DNA technology.

Regranex is recombinant human PDGF, which is active early in the process of ulcer healing. This medication is used to treat certain foot/leg ulcers in people with diabetes. It is used along with good foot/leg care such as keeping pressure off the wound to help the ulcer heal completely.Regranexworks by attracting certain natural substances to the ulcer that help wound healing. Regranex is the first drug that can be applied directly to the ulcer that is designed to promote healing. Regranex promotes the division of cells and the formation of new skin.

How to Use Regranex Cream

Wash hands thoroughly before applying this medicine. To avoid contaminating the container tip, do not touch it to the skin or any other surface. Learn all preparation and usage instructions in the product package. If any of the information is unclear, consult your doctor or pharmacist. The amount of the medication applied is based on the size of the ulcer. Your doctor or wound specialist should adjust your dose every 1 to 2 weeks. Squeeze the prescribed amount of medication onto a clean, firm, and non-absorbent surface like waxed paper. Use a clean applicator such as cotton swab, tongue depressor to apply a thin layer of the medication evenly over the ulcer, usually once daily or as directed by your doctor. Cover the ulcer with wound dressing as directed by your doctor. After 12 hours, remove the dressing, rinse the ulcer, and apply new dressing on the ulcer. Do not apply more medication at this time. Use this medication regularly in order to get the most benefit from it.

Cautions before Use Regranex Cream

The cautions, which are to be taken with Regranex skin cream, are as follows:

  • Pregnant women and breastfeeding mothers should take care before using this medication.
  • Before using this medication, tell your doctor if you havecanceror a history of cancer.
  • Before using Regranex tell your doctor or pharmacist if you are allergic to Becaplermin; or to other ingredients in this product like, parabens or if you have any other allergies

Regranex Cream Side effects

The side effects, which may occur due to the usage of Regranex skin cream, are as follows:

  • Extreme Dizziness
  • Allergic rashes
  • Swelling of face , throat and lips
  • Itching on the skin
  • Burning on the skin

Regranex Cream Reactions and Overdose

Before using this medication, ask your doctor or pharmacist about all prescribed drugs and nonprescribed or herbal products you are using as it may cause reactions with them.

Regranex skin cream may be harmful if swallowed. If overdose or swallowing is suspected the patient should be taken to the medical center immediately.


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