Generic Name:Thermazene

Thermazene is a skin treatment drug used for the treatment of various minor and major skin problems. This medication is used with other treatments to help prevent and treat wound infections in patients with serious burns. Thermazene works by stopping the growth of bacteria that may infect an open wound. This helps to decrease the risk of the bacteria spreading to surrounding skin, or to the blood where it can cause a serious blood infection called sepsis. It has the active ingredient of Silver sulfadiazine which belongs to a class of drugs known as sulfa antibiotics. Thermazene must not be used on premature babies or on newborns during the first 2 months of life because of the risk of serious side effects. This drug may also be used to help prevent and treat other skin and wound infections such as skin ulcers.

How to use Thermazene Cream

  • This medication is for use on the skin only. Your health care professional will clean and remove the dead tissue from the wound to help the healing process.
  • Apply this medication to the wound using sterile technique such as wearing sterile gloves and using sterile application tools, as directed by your doctor, usually 1 to 2 times daily.
  • The layer of medication should be about one-sixteenth of an inch thick or as directed. The wound should be covered with the cream at all times. Dressings may be applied over the cream, but only if needed.
  • If some of the cream rubs off the wound, reapply it immediately. The cream should also be reapplied immediately after hydrotherapy.
  • Treatment usually continues until the wound is completely healed or until the site is ready for skin grafting.

Cautions before Use Thermazene Cream

  • Before using Thermazene, tell your doctor or pharmacist if you are allergic to the active ingredient other sulfa antibiotics such as sulfamethoxazole then you should not use this medication.
  • People having a medical history of certain enzyme deficiency of G6PD or glucose-6-phosphate dehydrogenase deficiency should avoid
  • People having a medical history of kidney problems should not use Thermazene.
  • People having a medical history of liver problems are advised to not to use this medication
  • People having a medical history of low white blood cells should avoid using Thermazene.
  • Pregnant women and breastfeeding mothers should avoid this medication.

Thermazene Cream Side Effects

These side effects, which may occur due to usage of Thermazene are as follws:

  • Pain, burning, or itching of the treated skin
  • Skin and mucous membranes (such as the gums) may become blue or gray in color
  • Fever, chills, persistent sore throat
  • Easy bruising bleeding
  • Signs of anemia
  • Constant nausea vomiting
  • Dark urine
  • Yellowing of eyes and skin
  • Mental or mood changes
  • Allergic rashes
  • Severe Dizziness
  • Swelling of face, throat and mouth

Reactions and Overdose of Thermazene Cream

There are some products that may interact with this drug include cimetidine, certain drugs used to treat diabetes sulfonylureas such as glipizide,glyburide , phenytoin, skin products containing sodium sulfacetamide, enzyme products used to break down and remove dead skin/tissue from burns and wounds thus you should consult with your doctor before taking this drug into usage.

Dangerous overdose affects may rise if swallowed, if this happens the patient must seek medical care.


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