Generic Name:BCG Vaccine

TheraCys is a prescribed medication used commonly known as BCG vaccine. This medication is used to treat a certain type of bladder cancer (carcinoma in situ-CIS) and prevent it from returning. It is also used to prevent another type of bladder cancer (papillary tumor) from returning after surgery to remove it. This medication works by causing the body's defense system or immune system to become more active. This form of the medication is not used to prevent tuberculosis. This medication is injected directly into the bladder, where it causes inflammation and increases certain white blood cells known as natural killer cells. These killer cells act to destroy invading cells such as tumor cells in the bladder.

How to Use TheraCys BCG Injections

  • This medication is given into the bladder through a tube (catheter) as directed by your doctor. Do not give this medication by injection.
  • This medication is usually given weekly for the first 6 weeks and then less often thereafter as directed by your doctor. Do not drink any fluids for 4 hours before treatment.
  • The medication is left in the bladder for up to 2 hours and then released by urinating. Follow your doctor’s instructions carefully.
  • Since the urine contains live bacteria that may infect you or others, you must sit down to urinate for 6 hours after treatment to avoid splashing of the urine.
  • After each time you urinate during this 6-hour period, pour household bleach (about the same amount of bleach as the amount of urine) into the toilet, and then wait 15 minutes before flushing. Always wash your hands afterward.

Cautions before Use TheraCys BCG Injections

  • People suffering from a weak immune system from diseases such as AIDS, leukemia, or lymphoma are advised to not to take this vaccine.
  • Patients suffering from fever, a bladder infection, or blood in your urine are advised to avoid this injection from taking.
  • If you are using steroids or receiving chemotherapy or radiation treatments then try to avoid this immunization.
  • If you have had a bladder biopsy, surgery, or catheter within the past 14 days then make sure that you do not take this injection.
  • People with a medical history of certain blood vessel disease (aneurysm) are advised to not to take this medication.
  • People who are carrying man-made medical devices in the body such as pacemakers, artificial joints, arterial grafts should take proper precautions before taking this medication.

TheraCys BCG Injections Side Effects

The side effects which may arise due to the usage of TheraCys are as follows:

  • Pain or burning when you urinate
  • Difficulty in urination
  • More frequent or urgent urinating
  • Blood in your urine
  • Lower back pain
  • Pain or swelling in your testicles
  • Easy bruising or bleeding
  • Eye pain, redness, watering, severe burning or itching
  • Vision changes, increased sensitivity to light

Interactions and Overdose of TheraCys BCG Injections

TheraCys may interact with antibiotics such as isoniazid, rifampin, penicillin products such as amoxicillin, macrolides such as erythromycin, drugs that weaken the immune system such as abatacept, efalizumab, corticosteroids such as prednisone, cancer chemotherapy), mefloquine.

Overdose symptoms may include signs of an infection, such as fever, chills, body aches, weakness, or other flu symptoms.


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