V Gan 25

Generic Name: Promethazine

V Gan -25 is a prescribed medicine which is used to treat nausea and vomiting related to certain conditions mostly after surgery, motion sickness. The active ingredient of this medicine is Promethazine which has been licensed to treat nausea, motion sickness, and various other conditions. It is available by prescription only and comes in tablet, rectal suppository, syrup, and injectable form. By blocking histamine and acetylcholine receptors, the drug causes several different effects in the body and brain.

V Gan -25 is an antihistamine medically known as phenothiazine type. It works by blocking a certain natural substance that your body makes during an allergic reaction. Its other effects (e.g., anti-nausea, calming, pain relief) may work by affecting other natural substances and by acting directly on certain parts of the brain. This medication should not be used in children younger than 2 years. It may also be used before or after surgery, other procedures, or labor and delivery to help you feel calmer, to prevent nausea and vomiting, and to help certain narcotic pain relievers.

How to Use V Gan 25 Injection

  • This medication comes in tablet, rectal suppository, syrup, and injectable form. It is usually taken one to three times daily.
  • You can take a dose of promethazine with or without food.
  • If you are using the injection then inject this medication deep into a muscle. It may also be injected slowly into a large vein but not in the hand or wrist. V Gan-25 injection should be directly injected into a muscle, and this is the preferred way to give the medicine in most situations.

Cautions before Use V Gan 25 Injection

  • Children with Reye’s syndrome or liver disease should not take this medicine.
  • V Gan-25 can cause drowsiness and may impair your mental and physical ability to drive, operate heavy machinery, or perform other similar tasks.
  • This medicine can cause potentially fatal slow or irregular breathing. For this reason, people with COPD or sleep apnea should avoid this medication in most circumstances.
  • This drug can increase the risk of seizures.
  • V Gan-25 can impair the ability of the bone marrow to produce blood cells. This may be especially problematic for people undergoing chemotherapy or radiation therapy.
  • This medicine can cause a life-threatening condition called neuroleptic malignant syndrome (NMS).

V Gan 25 Injection Side Effects

The side effects which may arise with the usage of V Gan-25 are as follows:

  • Seizures
  • Hallucinations
  • Hyperactivity
  • Involuntary muscle movements
  • Frequent infections or easy bruising or bleeding, which may be signs of blood cell problems
  • Yellow skin (jaundice)
  • A protruding tongue
  • Strange eye movements or positioning
  • Slow or irregular breathing
  • High blood pressure (hypertension) or low blood pressure (hypotension)
  • A rapid heart rate

V Gan 25 Injection Interactions and Overdose

A number of medications may cause promethazine drug interactions, including CYP 2D6 and 2B6 inhibitors, anticholinergic drugs, acetylcholinesterase inhibitors, and epinephrine. Taking promethazine with these medicines can decrease the effectiveness of the drugs or increase your risk of side effects.

Symptoms of overdose of V Gan-25 may include slow or shallow breathing, deep sleep, seizures, muscle spasms, flushing, and widened pupils. These overdose symptoms should be taken under strict medical supervision.


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