Generic Name:Edrophonium

Tensilon is a prescribed mediation used for the treatment of Myasthenia gravis diagnosis in muscles. It has the active ingredient of Edrophonium is a type of medicine called an anticholinesterase. It works by prolonging the action of a neurotransmitter called acetylcholine. In the condition called myasthenia gravis the body's immune system destroys many of the acetylcholine receptors on the muscle cells. This means that the muscle becomes less responsive to nerve messages and as a result, the person experiences muscle weakness, particularly when they repeatedly try to use the same muscle. Tensilon stops cholinesterase from breaking down acetylcholine at the junctions between the nerves and the muscle cells. This prolongs the action of acetylcholine at the nerve endings and gives it more chance to act on the remaining acetylcholine receptors. Tensilon thus increases the likelihood of a nerve signal being successfully transmitted to the muscle. It improves nerve transmission to the muscles and allows these muscles to function normally.

How to use Tensilon Tablets

  • Tensilon is given as an injection through a needle placed into a muscle or vein. You will receive this injection in a clinic or hospital setting as part of a medical test.
  • When used in diagnosing myasthenia gravis, Tensilon is given in small doses over 15 to 45 seconds. After each dose you will be observed for the expected reaction to this medication (muscle twitching, vision changes, increased muscle weakness, sweating, stomach cramps, nausea, and other symptoms

Cautions before Use Tensilon Tablets

  • People who have recently had a heart attack or with a with a slow heart rate (bradycardia) are suggested to not to take this medication.
  • People with a decreased kidney function are suggested to not to take this drug.
  • People suffering from epilepsy are advised to not to take Tensilon.
  • People with a physical blockage in the gut (intestinal obstructions are restricted from using Tensilon.
  • People with a physical blockage in the urinary tract or urethral obstruction should not take this medicine.
  • People with a problem of Peptic Ulcer are advised to not to take Tensilon.
  • If you are allergic to sulfites then you should not take this medication.

Tensilon Tablets Side Effects

The side effects which may arise due to the usage of Tesilon are as follows:

  • Slow heart rate
  • Chest pain, weak pulse
  • Increased sweating, and dizziness
  • Feeling like you might pass out
  • Weak or shallow breathing
  • Urinating more than usual
  • Seizures (convulsions)
  • Trouble swallowing

Interactions and Overdose of Tensilon Tablets

This medicine may react with antimuscarinic medicines for Parkinson’s symptoms, eg procyclidine, orphenadrine, trihexiphenidyl, antimuscarinic medicines for urinary incontinence, such as oxybutynin, trospium, tolterodine, Atropin and Hyoscine.

Overdose symptoms of Tensilon may include nausea, vomiting, diarrhea, sweating, slow heart rate, and increased salivation (drooling) and in these conditions people should seek prompt medical support.


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