Generic Name:Triamterene

Triamterene is a potassium-sparing diuretic or water pill which prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

Triamterene is used to treat fluid retention in people with congestive heart failure, cirrhosis of the liver, or a kidney condition called nephrotic syndrome.

Triamterene is also used to treat edema caused by having too much aldosterone in your body. Aldosterone is a hormone produced by the adrenal glands to help regulate the salt and water balance in your body.

Triamterene can be taken with a full glass of water orally. Take this medication after eating a meal.

Triamterene consist of the active ingredient of Triamterene.

Triamterene Tablet Uses

  • Treating swelling (edema) associated with conditions such as congestive heart failure, cirrhosis of the liver, and certain severe kidney problems (eg, nephrosis).
  • Triamterene is a potassium-sparing diuretic. It works by making the kidneys eliminate sodium (salt) and water from the body while retaining potassium.

Cautions before Use Triamterene Tablets

Warnings and precautions to be aware of prior to taking triamterene include the following:

  • Triamterene can cause high potassium levels (hyperkalemia).
  • If you notice any symptoms of a possible electrolyte imbalance, contact your healthcare provider. These symptoms may include:
  • Abnormal sensations, such as burning, tingling, or pricking
  • Muscle weakness
  • Low heart rate (bradycardia).
  • Do not use salt substitutes while taking triamterene. Salt substitutes usually contain potassium, and combining them with triamterene can increase the risk of high potassium levels in your blood (hyperkalemia). Herb-type salt substitutes that do not contain potassium are okay to use.
  • Triamterene has been reported to cause kidney stones.
  • Triamterene is also known to worsen gout.
  • Triamterene may cause high blood sugar (hyperglycemia) in people with diabetes.
  • Triamterene is considered a pregnancy Category C medication. This means that it may not be safe to use during pregnancy.
  • It is not known if triamterene passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before using the drug (see Dyrenium and Breastfeeding).
  • Triamterene may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.

Triamterene Tablets Side Effects

Triamterene is likely to cause

  • High blood potassium levels that can be fatal if not corrected.
  • If you develop muscle weakness or irregular heartbeat, notify your doctor immediately.

Never use Triamterene Tablets if:

  • you are allergic to any ingredient in Triamterene
  • you are taking potassium supplements, another potassium-sparing diuretic (eg, amiloride), or an aldosterone blocker (eg, eplerenone)
  • you are unable to urinate or have high blood potassium levels or severely decreased liver or kidney function
  • Triamterene may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Triamterene with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Tell your doctor or dentist that you take Triamterene before you receive any medical or dental care, emergency care, or surgery.
  • Use Triamterene with caution in the Elderly; they may be more sensitive to its effects.
  • Triamterene should not be used in Children; safety and effectiveness in children have not been confirmed.
  • Pregnancy and Breast-Feeding: It is not known if Triamterene can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Triamterene while you are pregnant. It is not known if Triamterene is found in breast milk. Do not breast-feed while taking Triamterene.

Triamterene Tablets Interaction

When certain medications are taken together with Triamterene, drug interactions could occur that may affect the effectiveness of the medicines or increase your risk for side effects. Medications that may cause to react negatively Triamterene interactions include Accupril, Accuretic and Aceon, amongst others.

Triamterene Tablets Overdose Symptoms

Symptoms of a triamterene overdose may include increased urination, nausea, vomiting, weakness, fever, warmth or flushing in your face, or muscle spasms.


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