Generic Name:Hyaluronidase Injection

Vitrase is a prescribed medication used to treat your body to absorb injections. It has the active ingredient of Hyaluronidase which is a genetically designed protein. This medication is an enzyme used to help the body absorb other medications such as anesthetics or water preparations  medically known as hypodermoclysis that are given by injection either under the skin such as subcutaneously, or intradermal commonly known into the muscle (IM). Vitrase is also used to help contrast dyes in your body show more clearly on certain types of x-rays or scans.

How to Use Vitrase Injections

  • Follow all instructions for the proper mixing and dilution with correct IV fluids. If you don’t know the processes then refer your chemist.
  • A skin test is recommended before the first dose to test for sensitivity to this medication. Consult your doctor or pharmacist for details. Give this medication by injection directly under the skin (subcutaneously) or into a muscle (IM), or as directed by the doctor.
  • This medication should not be given into the vein (IV). This medication may be directly added (mixed) with other medications prior to injection and make sure that you take this under medical supervision.
  • This medication should be checked visually for particles or discoloration before use. If present, do not use the liquid.

Cautions before Use Vitrase Injections

  • Women who are pregnant or breastfeeding should take proper advice from their healthcare advisors before taking this medication.
  • People with a medical history of cancer or presently suffering from it should not take this medication.
  • People who are allergic to the active ingredient of the medicine should not take it.

Vitrase Injections Side Effects

The side effects which may arise due to the usage of Vitrase are as follows:

  • Rash
  • Itching
  • Swelling
  • Dizziness
  • Trouble in breathing
  • Redness or swelling at the injected area

Interactions and Overdose of Vitrase Injections

Vitrase may react with furosemide (Lasix), phenytoin (Dilantin), a sedative or anxiety medication such as Valium, Xanax, Tranxene, aspirin or salicylates, cortisone or ACTH (Corticotropin), estrogens, an antihistamine such as a cold or allergy medicine. This medicine may also react with a local anesthetic called Lidocaine,

In case of over dosage with Vitrase patient should seek immediate medical support.


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